Solving Local Problems with National Reach

Discover emerging regional ecosystems turning Tough Tech into lasting change.

Discover who's shaping the future
Colorado and Wyoming
Colorado and Wyoming
NSF ASCEND Engine
Turning data into action for community resilience.
The NSF ASCEND Engine is accelerating the development, testing, and scaling of next-generation technologies that will empower communities to better monitor, protect against, and adapt to the increasingly threatening impacts of weather-related natural hazards in the midwest region.
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North Dakota
North Dakota
NSF AgTech Engine
Powering ideas that feed the world.
The NSF AgTech Engine in North Dakota is fueling the development and commercialization of new technologies that will significantly improve the growth of new and existing U.S. crops, with the potential to revolutionize the way America produces food for the world.
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Upstate New York
Upstate New York
NSF Energy Storage Engine
Powering America’s battery future.
The Upstate New York Energy Storage Engine is powering an emerging, thriving ecosystem for advanced battery technology innovation and production, driving economic growth and reestablishing U.S. leadership in energy storage.
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Louisiana
Louisiana
NSF FUEL Engine
Future-proofing the energy economy in Louisiana, for the world.
The NSF FUEL Engine is commercializing innovative carbon management technologies and building a skilled workforce to fuel the next generation of energy and chemical manufacturing in Louisiana - providing energy security for the nation and the world.
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Central Florida
Central Florida
NSF Florida Semiconductor Engine
Shaping the future of semiconductor technology for the nation.
The NSF Florida Semiconductor Engine is developing the next generation of specialty and advanced semiconductor packaging technologies - bolstering national security and transforming Florida’s economic landscape.
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Southwest
Southwest
NSF Futures Engine
Safeguarding the U.S. southwest through deep tech innovation.
The NSF Futures Engine is advancing the commercialization of promising new technology that will stabilize water and power supplies across the desert states, ensuring the region can continue to support rapid economic growth in key tech and manufacturing sectors.
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North Carolina
North Carolina
NSF Regenerative Medicine Engine
A new national model for regenerative medicine innovation and economic revitalization.
The NSF Regenerative Medicine Engine is advancing the commercialization of new, lifesaving regenerative medicine technology - with the potential to transform the way our nation approaches tissue repair, disease treatment, and organ replacement.
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North Carolina
North Carolina
NSF Textile Innovation Engine
Transforming and safeguarding the fabric of our nation.
The NSF Textile Innovation Engine is using creative new coalitions, skills-based training programs, and innovations in technology to grow an emerging innovation ecosystem that will reimagine and revitalize textile research, development, and production in the southeast region.
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Great Lakes
Great Lakes
NSF Water Innovation Engine
Turning waste into wealth.
The NSF Water Innovation Engine in the Great Lakes is powering the commercialization of innovative new technologies to extract valuable minerals and toxic chemicals from U.S. water supplies - securing domestic supply chains and safeguarding vital national security assets.
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