Solving Local Problems with National Reach

Discover emerging regional ecosystems turning Tough Tech into lasting change.

Discover who's shaping the future
Colorado and Wyoming
Colorado and Wyoming
NSF ASCEND Engine
Turning data into action for community resilience.
The National Science Foundation (NSF) Advanced Sensing and Computation for Environmental Decision-making (ASCEND) Engine in Colorado and Wyoming is advancing technologies and data-driven systems that help communities better predict, prepare for, and respond to natural hazards.
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North Dakota
North Dakota
NSF AgTech Engine
Powering ideas that feed the world.
The NSF AgTech Engine in North Dakota is fueling the development and commercialization of new technologies that will significantly improve the growth of new and existing U.S. crops, with the potential to revolutionize the way America produces food for the world.
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Upstate New York
Upstate New York
NSF Energy Storage Engine
Powering America’s battery future.
The National Science Foundation (NSF) Energy Storage Engine in Upstate New York is strengthening America’s battery industry through the development and production of next-generation energy storage materials and technologies.
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Louisiana
Louisiana
NSF FUEL Engine
Future-proofing the energy economy in Louisiana, for the world.
The NSF Future Use of Energy in Louisiana (FUEL) Engine is advancing technologies that improve the efficiency, safety, and performance of energy operations, while expanding regional economic opportunity.
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Central Florida
Central Florida
NSF Florida Semiconductor Engine
Shaping the future of semiconductor technology for the nation.
The NSF Florida Semiconductor Engine is developing the next generation of specialty and advanced semiconductor packaging technologies - bolstering national security and transforming Florida’s economic landscape.
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Southwest
Southwest
NSF Futures Engine
Safeguarding the U.S. southwest through deep tech innovation.
The NSF Futures Engine is advancing the commercialization of promising new technology that will stabilize water and power supplies across the desert states, ensuring the region can continue to support rapid economic growth in key tech and manufacturing sectors.
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North Carolina
North Carolina
NSF Regenerative Medicine Engine in North Carolina
A new national model for regenerative medicine innovation and economic revitalization.
The National Science Foundation (NSF) Regenerative Medicine Engine in North Carolina is advancing lifesaving regenerative medicine technologies by equipping companies with the resources and partnerships needed to build, grow, and scale.
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North Carolina
North Carolina
NSF Textile Innovation Engine
Transforming and safeguarding the fabric of our nation.
The NSF Textile Innovation Engine is using creative new coalitions, skills-based training programs, and innovations in technology to grow an emerging innovation ecosystem that will reimagine and revitalize textile research, development, and production in the southeast region.
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Great Lakes
Great Lakes
NSF Water Innovation Engine
Turning waste into wealth.
The National Science Foundation (NSF) Great Lakes RENEW Engine (Recovery of Energy, Nutrients, Critical Elements, and Water) is advancing new solutions to remove harmful contaminants and recover valuable resources from water - effectively turning waste into wealth for the Great Lakes region.
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