Spotlight
9.14.2025
Diana
Kamau

NSF Engine Spotlight: Piedmont Triad Regenerative Medicine (PTRME) Engine

The Piedmont Triad Regenerative Medicine (PTRME) Engine, led by the Wake Forest Institute for Regenerative Medicine (WFIRM), is dedicated to building an innovation ecosystem that drives workforce development, job creation, and economic growth in the regenerative medicine industry.

Focused on the Piedmont Triad region (Greensboro, Winston-Salem, and High Point, NC), the NSF Engine is advancing technologies that advance regenerative medical technologies based on industry-use inspired research, technology translation, and workforce development to enhance the ability to replace or restore damaged tissues and organs, positioning the area as a leader in this emerging field.

With more than 150 partners—including North Carolina Agricultural and Technical State University (NC A&T), Forsyth Technical Community College, and Winston-Salem State University (WSSU)—the Engine integrates collaboration between academia, industry, and government entities such as Axiom Space, ISSNL, and NASA. By leveraging these partnerships, it aims to foster economic development through rapid commercialization of regenerative medicine and build a resilient symbiotic relationship between industry, academics, and governmental entities.

 

Core Objectives of the Piedmont Triad Regenerative Medicine NSF Engine:

  •       Innovation and Technology Translation: Through its Innovation, Translation, and Education Cores (ITECs), the Engine focuses on developing regenerative medicine solutions in areas such as biological raw materials, biomaterials, bioengineering, and terrestrial and in-space biomanufacturing. This structure accelerates the transition of cutting-edge regenerative technologies into commercial-ready market-ready products.
  •       In-Space and Terrestrial Biomanufacturing: In partnership with companies focused on biomanufacturing scale, supply chain capability, and workforce development coupled with Axiom Space ISSNL, and NASA, the Engine explores translation of regenerative technology, tissue, and organ regeneration in multi-gravity conditions providing a unique opportunity to push regenerative medicine technologies beyond traditional limits.
  •       Workforce Development: Collaborating with NC A&T, WSSU, Wake Forest University, and Forsyth Tech, the Engine is committed to building a diverse talent pool to support commercialization of regenerative technologies.  The Engine offers training programs that range from micro-certifications to advanced degrees, with a focus on supporting underrepresented populations in STEM fields.

Under the leadership of CEO Dr. Tim Bertram, Chief Innovation Officer Dr. Anthony Atala, Chief Operating Officer Dr. Jesse Thornburg, and Translational Lead Dr. Steven Bauer, the Piedmont Triad Regenerative Medicine Engine is positioned to transform commercialization of regenerative medicine while strengthening the regional economy. Through targeted innovation, strategic partnerships, and workforce development, the Engine is advancing U.S. leadership in this critical industry while addressing healthcare challenges at a national level. Visit their website regenmedengine.com to learn more!

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